What Are The Best Nitric Oxide Supplements in 2017?

Athletes and bodybuilders have been using nitric oxide in their pre-workout routines for over two decades. Recent studies have shown that nitric oxide boosters have the potential to take your game to the next level. (source) These studies could be partly responsible for their increased popularity among the average consumer recently.

With the rise in demand, more manufacturers are coming out with new nitric oxide supplements - and it can be difficult to sift through them all. In order to help make your decision easier, I’ll share my picks for the best nitric oxide supplements out there.

You’ll find out the pros and cons to each brand and I’ll reveal my own personal favorite nitric oxide supplement at the end.

What is Nitric Oxide?​

Nitric oxide is an important molecule that helps the cells of your body to communicate. It plays a critical role in blood pressure and overall blood circulation. (source) Nitric oxide penetrates underlying smooth muscles in the arteries and helps dilate and relax them.

Increasing nitric oxide production can help improve your health in a number of ways. Nitric oxide can contribute to treating everything from erectile dysfunction to dementia to even fighting off cancer cells. (source 1, 2)

Advantages of Nitric Oxide Supplements​

There are numerous advantages to using nitric oxide as a pre-workout booster. Let’s take a closer look at some of the main reasons nitric oxide is becoming a favorite among athletes and bodybuilders alike.

  • Nitric oxide can lead to increased endurance and strength. Several studies have shown that nitric oxide can enhance oxygen and nutrient delivery to active muscles. The added nutrients can improve both muscle performance and recovery. (source)
  • Nitric oxide keeps your heart healthy. Evidence suggests that nitric oxide plays a significant role in blood pressure levels. (source) L-arginine found in nitric oxide boosters is known to help dilate your arteries resulting in lowered blood pressure. Note that if you’ve been diagnosed with low blood pressure, a nitric oxide supplement may not be safe.

To find out more about how nitric oxide can boost your workouts to the next level, take a look at this short YouTube video.

Tips on How to Take Nitric Oxide Supplements

Nitric oxide is best when used as a pre-workout supplement. Use the following tips to get the most out of your workout routine.

  • Take your nitric oxide supplement approximately 30 minutes before your workout.
  • Drink lots of water when taking nitric oxide to help absorption.
  • Don’t give up too soon if you don’t notice an improvement right away. It can take up to four weeks to see results from your nitric oxide booster.
  • Use caution when stacking nitric oxide with any other pre-workout pills, powders, or shakes.
  • Start out slowly. Even if you are a nitric oxide pro, it may take several days to adjust to a new version.

Bear in mind that each supplement (and each user!) is unique. Be sure to read the manufacturer’s packaging and follow recommended dosages and directions as closely as possible for best results. If you’re not sure about something, check with a healthcare professional.

Ingredients in the Best Nitric Oxide Supplements

There are several main active ingredients in the best nitric oxide supplements. We’ll take a closer look at some of the ingredients that are must-haves when it comes to choosing one that will work for both your needs and your wallet.


L-arginine is an amino acid that your body turns into the chemical nitric oxide. Nitric oxide then causes blood vessels to open wider resulting in improved blood flow. (source)

Many l-arginine strains have been developed with the goal of improving nutrient absorption, resulting in enhanced effects. Though efficacy is not yet proven, there are two main types of l-arginine; l-arginine and l-arginine alpha-ketoglutarate (A-AKG). So, what’s the difference?

Essentially, when a nitric oxide supplement has l-arginine AKG, you are getting two for one.

AAKG is added to many fitness supplements due to its superior ability to rapidly increase blood circulation. It is also a larger proponent of increased energy levels once it enters the Krebs cycle. (source)

Your body will break down both substances separately and allow them to work together to create the ideal performance.

If the nitric oxide booster you’ve decided on doesn’t have the added AKG strain, you can take it separately. It will work the same whether ingested together in one pill or on their own.


L-citrulline is a naturally occurring amino acid that is found in certain foods. However, it is also produced in small amounts in the body. (source) It acts as a booster for nitric oxide and helps it perform better.

Once absorbed, our bodies change l-citrulline into l-arginine as well as nitric oxide. It then has the ability to open veins and improve blood circulation.

L-citrulline is used to help build muscles and improve overall athletic performance. However, some studies show that l-citrulline doesn’t work as well for well-trained athletes (source) Instead it’s better to use this amino acid to help boost your initial training and performance.


Yohimbe is replacing caffeine in many new supplements on the market these days, and it’s easy to see why. Yohimbe is an all-natural plant-based stimulant. Usually, it is derived from the root or the bark of an evergreen tree found in central and western parts of Africa. (source)

Yohimbe is used to treat many disorders such as depression, erectile dysfunction, athletic performance and weight loss. (source)

It works to stimulate your central nervous system as well which can assist in giving you the focus and motivation you need to power through your workout.

It is worth noting, however, that preliminary research has yet to prove that yohimbe improves performance or builds muscle.

The Best Nitric Oxide Supplements Reviewed

You should now have a better idea of what you want to get out of your nitric oxide booster. Take a look at some of the following reviews to determine which will work best for your needs.

Each of these nitric oxide supplements has advantages. However, they all have some drawbacks as well. Take the time to read through each one before making your final decision. Otherwise, you may end up with buyer’s regret.



Our rating

An ultra-concentrated tablet that gives you one of the highest potencies of nitric oxides on the market. Take two pills with your pre-workout shake 30-40 minutes before exercise for the boost you need.

The advanced arginine blend focuses on muscle regeneration and circulation. You will notice increased stamina, bigger pumps and better blood circulation for a longer period.

Made with three different types of arginine, each is designed to function slightly differently. Citrulline is used to amplify the results of the arginine, so you have the best performance possible.

You should be able to begin seeing more definition and better overall results when leaving the gym in about three weeks.

This supplement claims to allow more oxygen into your muscles, so you have a quicker cooling time. The energy you save from that cool down could be used elsewhere, with the ultimate goal being to maximize your workout.

Faster recovery time would also mean getting back into the gym sooner.

This supplement doesn’t have any added stimulants. You won’t feel as much energy and focus as you would with others. However, it also doesn’t have the headaches or dizziness associated with supplements that have added stimulants such as caffeine.

Arginine promotes a healthy heart. Without the use of stimulants, this supplement might be one of the best choices for people with high blood pressure. However, you should first consult with your physician to ensure that you can safely use a supplement containing arginine

Although you only need to take two of these high potency pills to get desired results, they can be difficult to swallow. Not only are they quite large, but they taste horrible as well. Take them with your shake or morning juice.


  • Works for hours
  • Increased stamina
  • Improved recovery time
  • Faster gains
  • 3 types of arginine
  • Citrulline amplifies results
  • Only 2 tablets per serving
  • Made in the USA


  • If you’re seeking a stimulant, this product doesn’t contain any
  • Users reported an unpleasant taste



Our rating

This product from Sheer Strength Labs is a pre-workout nitric oxide supplement that works alongside your body to give you the most out of your exercise routine. Take the Nitric Oxide Booster 30 minutes before your workout with a good bit of water and off you go.

L-arginine may aid blood flow in the arteries of the heart. Improved blood flow is beneficial, as it can alleviate symptoms of clogged arteries. (source) .

Very few other nitric oxide supplements take advantage of l-citrulline as well as this one does. L-citrulline offers an extra boost to the nitric oxide so that you can build muscle and mass faster.

You will likely notice more vascularity as you work out. However, it may take up to four weeks to see any real definition forming.

Some users have claimed that there is no noticeable boost in stamina, which may make this supplement better for hitting the gym rather than going for a run. While lifting you may feel a bigger pump sensation during your workout.

Because there are no added energy enhancers to this drug such as caffeine, or yohimbe, you won’t notice a crash like similar products.

You may prefer to cycle this nitric oxide supplement. However, because it works naturally with your body as it exercises, it is not necessary. The potency won’t drop over time.


  • Heart healthy
  • Increased muscle growth
  • It contains N.O. booster l-citrulline
  • Bigger pump during workout
  • Ideal for lifting
  • Better recovery
  • Easy to swallow capsule
  • No crash


  • No stimulant added
  • Four pills per dose
  • Users reported that it took four weeks to see any results
  • Not vegan



Our rating

With the patented extended release formula of these caplets you know you are getting a potent dosage throughout the day. The NOS enhancing fraction increases the baseline of nitric oxide up to 950% above the average brand.

Alpha-lipoic acid is used in this nitric oxide supplement to boost your insulin sensitivity so you can have a better nutrition uptake.

Unlike some other supplements on the market today, you will feel the effects almost immediately. You will notice a tingling sensation through your muscles as your blood flow is increased throughout the day.

Made with high-end ingredients such as 3000mg of arginine alpha-ketoglutarate (A-AKG), you know it’s powerful. These caplets claim to increase strength, which could help you take your workout to the next level.

With the combination of increased strength and blood circulation, you can gain muscle mass at a faster rate.

There are several downsides you should be aware of when thinking about this powerful supplement. Because it is so intense of a sensation, you may want to start gradually until your tolerance builds up. Otherwise, you may find yourself with a back headache when the caplets wear off.

Although there are more pills per bottle than other supplements, you still receive a 30 day supply. For men, the dosage is between 8-10 caplets per day based on weight. For women, the recommended dosage is between 4-6 based on weight.

The pills can be quite large and difficult to swallow as well. It’s up to you to decide if the large dose is worth the powerful affects you receive from this nitric oxide supplement.


  • Patented extended release
  • Immediate muscle sensation
  • Up to 950% stronger than regular pills
  • Increased strength
  • Improves blood flow
  • Good pump during workout


  • Higher serving size than most
  • Huge, uncoated caplets
  • Takes time to build up tolerance



Our rating

A nitric oxide supplement that will keep you mentally energized during your workout. Take these 30 to 45 minutes before your workout for best results.

Yohimbe root is a nice caffeine-free energy alternative that has the potential to drive you through your workouts with additional focus and efficiency.

Unlike other nitric oxide supplements, you can also use this as a dietary aid. It increases your glucose (sugar) uptake so that you can deplete fat storage quicker. Increased glucose uptake also assists in reducing your recovery time.

You may want to cycle yourself on these capsules depending on how they affect you over time. If you notice you need to take additional pills to feel the same sense of motivation, take a break from them for a while and restart.

You shouldn’t feel lightheaded or nauseated when you take this supplement which is somewhat common in nitric oxide boosters even when stacked.

The half-life of this supplement can be shorter than desired. You will feel a burst of energy for about 30 minutes, then it begins to taper off. After the initial 30 minutes, you will simply feel more focused on the task at hand.

Unfortunately, you don’t know exactly what you are getting with this supplement. All ingredients are listed as proprietary blends. It would be nice to know the individual dosages of each item on the list. However, many supplements are leaning towards protecting their blends this way.


  • Boost of energy from yohimbe root
  • Easy to swallow capsules
  • Promotes a healthy heart
  • Weight loss
  • Reduces fatigue
  • Improves recovery time
  • Increased focus and motivation
  • Made in the USA


  • Longer time to take effect
  • Short half-life
  • Large dosage of 4 capsules
  • Some users reported feeling jittery



Our rating

Made with five premium ingredients and GMP certified, you can be assured that this nitric oxide supplement is consistent and high-quality. Good Manufacturing Practice (GMP) certified products are controlled according to high quality standards, Furthermore, this product is made in an FDA regulated facility unlike some of its competitors.

The combination of niacin, arginine, l-citrulline and citrus aurantium are designed to give you the extra push you need. However, be aware that citrus aurantium, also known as “bitter orange,” does have some marked side-effects such as increased heart rate and high blood pressure. (source) The yohimbe in this supplement can give you a great amount of energy and focus.

Arginine is a heart healthy substance that also works to grow muscles faster when used correctly. Arginine may assist in increased endurance while decreasing recovery time.

The faster recovery is due to increased blood flow which in turn enhances oxygen absorption into your cells. Your muscles have a more rapid cool-down and are aching and swollen than normal.

The easy to swallow capsules result in a better absorption so you can feel results quicker. While other supplements take at least half an hour to take effect, these are felt almost immediately.

These pills have a highly powerful effect making you energized and focused on the task at hand. If you are sensitive to high-energy levels, you may want to start off slower than the recommended five pill dosage.


  • Made with 5 premium ingredients
  • Immediate results
  • Powerful energy boost
  • Fast recovery time
  • Heart healthy
  • GMP certified
  • Easy to swallow capsules
  • Made in the USA, in an FDA regulated facility


  • 5 pills per dosage
  • Too much energy for some

Final Thoughts

In the end, I’ve chosen the Maximus Nitric Oxide Tablets by Naturo Nitro to top the list in 2017. The overwhelming amount of features this ultra-concentrated table has are hard to beat. The limited drawbacks such as not having an added stimulant could actually be beneficial for some people.

Made with three different strains of arginine and completed with citrulline for an extra boost that lasts all day. This supplement works on muscle regeneration and circulation so that you can recover quickly and have rapid gains.

Ultimately, it is up to you to find the best nitric oxide supplement to fit both your needs and budget. With the help of this guide, you should be well on your way to making the right decision for your particular workout.

Helen Sanders

Chief editor here at Health Ambition, I'm a proud mother of two passionate about nutrition and ways to live healthier with more energy!

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